Research Trials

At the forefront of the field of psychedelic-assisted therapy, InnerMost is conducting a number of industry-sponsored and independently initiated clinical trials. Building on his 15 years of experience in psychedelic-assisted therapy research, Dr. Casey Paleos guides our research team as Principal Investigator in all current and future trials.

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UPCOMING CLINICAL TRIAL

Phase III Trial to Assess CYB003 in Major Depressive Disorder

Research into CYB003, a next-generation psilocybin analog,  is showing meaningful improvements for some individuals living with depression. This study offers an opportunity to explore how such treatment might support healing for those living with depression.

UPCOMING CLINICAL TRIAL

Phase III Long-Term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD

This is a long-term extension study that allows for open-label dosing or re-dosing—for participants who did not respond in the first two studies, or relapsed during the extension study. Participants will need to complete either of the first two CYB003 for MDD trials to participate.

UPCOMING CLINICAL TRIAL

MDMA-Assisted Psychotherapy for PTSD & Burnout in Frontline Healthcare Workers

Frontline healthcare workers endured extraordinary stress during the pandemic, and many continue to carry symptoms of trauma. This study seeks to explore whether MDMA-assisted therapy can provide meaningful relief and support for those who served in these critical roles.

All Upcoming and Completed Trials

Phase III Trial to Assess CYB003 in Major Depressive Disorder

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Phase III Long-Term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD

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MDMA-Assisted Psychotherapy for PTSD & Burnout in Frontline Healthcare Workers

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Phase III Clinical Trials for MDMA-Assisted Therapy for PTSD (MAPP 1)

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Phase III Clinical Trials for MDMA-Assisted Therapy for PTSD (MAPP2)

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Phase II Open Label Clinical Trial for MDMA-Assisted Therapy (MP 16)

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Phase III Open Label Crossover (MPLONG)

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Apply for a Trial at InnerMost

Explore our services in psychedelic-assisted therapy, clinical research, and therapist trainingdesigned to support your healing journey.

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Your questions, clearly answered

Explore common questions about participation in one of our research trials.

How do I apply to participate in  a research trial at InnerMost?
What is the goal of psychedelic-assisted therapy research trials at InnerMost?
Does it cost anything to participate in a research trial, and will I be compensated for participating?
Can I continue taking my psychiatric medications while participating in a research trial?
What support is provided during and after dosing?
Will I definitely receive psychedelic medicine during research trials at InnerMost?
Can I withdraw from the research trial if I no longer want to participate?
How can I find a trial that I am qualified for?
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